Fig. 14. Over-expression of PTEN expression with PTEN-GV141 inhibits the proliferation -associated protein of FLSs. (A) After FLSs were transfected with PTEN-GV141, and the protein levels of c-Myc, cyclinD1, and PCNA were analyzed by western blot. (B) AIA FLSs were transfected with PTEN-GV141, and the mRNA levels of c-Myc and cyclinD1 were analyzed by q-PCR. All values are expressed as mean ± SD. ^## P<0.01 vs. normal group; ^*P<0.05, ^**P<0.01 vs. AIA group.